Medical Dictionary

Letterer–Siwe disease

noun Let·ter·er–Si·we disease \ˈlet-ər-ər-ˈsē-və-\

Medical Definition of LETTERER-SIWE DISEASE

:  an acute often fatal disease of young children that is marked by proliferation of Langerhans cells and is characterized especially by fever, anemia, hepatosplenomegaly, and a eczematous skin rash

Biographical Note for LETTERER-SIWE DISEASE

Letterer, Erich (1895–1982), German physician. Letterer first described Letterer-Siwe disease in 1924. The author of several textbooks on pathology, he described the disease from the viewpoint of a pathologist.
Siwe, Sture August (1897–1966), Swedish pediatrician. Siwe presented another, independent description of Letterer-Siwe disease in 1933, this time from the clinical point of view.

Browse

May 25, 2015
callithump Hear it
a noisy boisterous band or parade
Take a 3-minute break and test your skills!
How to use a word that (literally) drives some people nuts.
Test your vocab with our fun, fast game
Ailurophobia, and 9 other unusual fears