: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue
Examples of leptin in a Sentence
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Most of his peers were focused on GLP-1, or leptin, or other peptides—molecules made of the same building blocks as proteins, but smaller.
—
Roxanne Khamsi, The Atlantic, 19 Nov. 2025
This brain signaling pattern reduced appetite independently of leptin, another satiety hormone.
—New Atlas, 14 Oct. 2025
In late September 2020, a Mass General endocrinologist called with the test results: Ben had a leptin deficiency.
—Wendy Grossman Kantor, People.com, 7 Aug. 2025
Sleep deprivation is also associated with disruptions in appetite-regulating hormones (ghrelin and leptin), which often increases cravings for sugary, nutrient-poor foods.12
2.
—Lauren Panoff, Verywell Health, 25 July 2025
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Roxanne Khamsi, The Atlantic, 19 Nov. 2025
This brain signaling pattern reduced appetite independently of leptin, another satiety hormone.
—New Atlas, 14 Oct. 2025
In late September 2020, a Mass General endocrinologist called with the test results: Ben had a leptin deficiency.
—Wendy Grossman Kantor, People.com, 7 Aug. 2025
Sleep deprivation is also associated with disruptions in appetite-regulating hormones (ghrelin and leptin), which often increases cravings for sugary, nutrient-poor foods.12
2.
—Lauren Panoff, Verywell Health, 25 July 2025
See All Example Sentences for leptin
Cite this Entry
“Leptin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leptin. Accessed 30 Nov. 2025.
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leptin
noun
lep·tin
ˈlep-tən 
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue
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