leptin

noun

lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

Examples of leptin in a Sentence

Recent Examples on the Web
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You Miss Your Body's Fullness Cues Eating too quickly may reduce your natural appetite regulation by rushing past fullness cues and reducing the release of ghrelin and leptin, essential hunger and fullness hormones. Brandi Jones, Verywell Health, 7 July 2025 For instance, some bacteria might influence how your body stores fat, regulate your appetite hormones (like leptin and ghrelin), and regulate your blood sugar levels.8 5. Qin Rao, Verywell Health, 4 June 2025 Ghrelin also works with leptin, another hormone, to regulate your appetite. Brittany Lubeck, Ms, Rdn, Verywell Health, 14 Apr. 2025 When dieting or losing weight, ghrelin levels tend to rise while leptin levels typically decrease.13 Essentially, ghrelin and leptin work together to control your appetite by sending hunger and satiety cues. Brittany Lubeck, Ms, Rdn, Verywell Health, 14 Apr. 2025 See All Example Sentences for leptin

Word History

Etymology

Greek leptos slender + English -in entry 1

First Known Use

1995, in the meaning defined above

Time Traveler
The first known use of leptin was in 1995

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Cite this Entry

“Leptin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leptin. Accessed 13 Jul. 2025.

Medical Definition

leptin

noun
lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

More from Merriam-Webster on leptin

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