isotretinoin

noun

iso·​tret·​i·​noin ˌī-sō-ˈtre-tə-ˌnȯin How to pronounce isotretinoin (audio)
: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

Examples of isotretinoin in a Sentence

Recent Examples on the Web Other acne treatment options include oral isotretinoin (Accutane) for severe acne and hormonal therapy such as spironolactone with oral contraceptives for girls with moderate acne. Casey Gallagher, Verywell Health, 2 Mar. 2024 However, some people still refer to isotretinoin as Accutane. Leah Ansell, Verywell Health, 24 Dec. 2023 Accutane was formerly a popular brand name of isotretinoin that's no longer being sold. Leah Ansell, Verywell Health, 24 Dec. 2023 Generally, people take isotretinoin two times daily for four to five months.8 Take isotretinoin after eating with a full glass of water. Madeleine Burry, Health, 19 Aug. 2023 Healthcare providers may advise trying an oral or topical prescription medicine, such as antibiotics, isotretinoin, or retinoids. Jacqueline Andriakos, Health, 25 Aug. 2023 Oral Retinoids Use isotretinoin as prescribed by a healthcare provider. Madeleine Burry, Health, 19 Aug. 2023 Oral prescription medications, such as antibiotics, spironolactone, and isotretinoin. Alyssa Hui, Verywell Health, 31 July 2023 Accutane, also referred to as isotretinoin (Accutane is the brand name for the drug isotretinoin), was first introduced in 1982 — so, almost a decade after Roe v. Wade was passed. Megan Decker, refinery29.com, 8 July 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'isotretinoin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1979, in the meaning defined above

Time Traveler
The first known use of isotretinoin was in 1979

Dictionary Entries Near isotretinoin

Cite this Entry

“Isotretinoin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isotretinoin. Accessed 19 Mar. 2024.

Medical Definition

isotretinoin

noun
iso·​tret·​i·​noin ˌī-sō-ˈtret-ə-ˌnȯin How to pronounce isotretinoin (audio)
: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

called also 13-cis-retinoic acid, retinoic acid

see accutane
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!