isoform

noun

iso·​form ˈī-sə-ˌfȯrm 

: any of two or more functionally similar proteins that have a similar but not an identical amino acid sequence

Examples of isoform in a Sentence

Recent Examples on the Web

Vitamin E has eight different isoforms, or types, and each may do slightly different things in our bodies. — Cosby Stone, The Conversation, 22 Nov. 2019

In the same way, a cell can join different exons together to form distinct versions of a protein, known as isoforms, each with its own shape and function. — William A. Haseltine, Forbes.com, 7 Apr. 2026

Some genes showed a shift in isoform usage (using different versions of the same gene), especially Homer1. — New Atlas, 16 Aug. 2025

Depending on which isoforms are affected, the accumulation of tau may present as one of more than 20 different tauopathies. — William A. Haseltine, Forbes, 25 Oct. 2024

Word History

First Known Use

1983, in the meaning defined above

Rhymes for isoform

• chloroform
• coliform
• cribriform
• cruciform
• filiform
• fusiform
• microform
• multiform
• outperform
• piriform
• plexiform
• pyriform

Medical Definition

isoform

noun

iso·​form ˈī-sə-ˌfȯrm 

: any of two or more functionally similar proteins that have a similar but not identical amino acid sequence and are either encoded by different genes or by RNA transcripts from the same gene which have had different exons removed