immunoproliferative small intestinal disease

immunoproliferative small intestinal disease

noun

Definition of IMMUNOPROLIFERATIVE SMALL INTESTINAL DISEASE

: a lymphoma that arises in the small intestine, is marked especially by abdominal pain, diarrhea, and malabsorption, is associated with the secretion by proliferating plasma cells of truncated IgA heavy chains without the accompanying light chains, and that chiefly affects individuals in Mediterranean regions—abbreviation IPSID; called also alpha chain disease, Mediterranean lymphoma