immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
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Harmful molecules called free radicals show up, certain enzymes start breaking down collagen and the immune system is activated. Leslie Baumann, Miami Herald, 9 July 2026 This loss is often the result of an autoimmune process in which the body's immune system mistakenly attacks those cells. Daryl Austin, USA Today, 8 July 2026 Doctors are also more likely to order the test for those at higher risk of complications from their infection, including very young babies and children, and people with weakened immune systems. Alice Park, Time, 8 July 2026 An air of credibility Peptides are a string of amino acids — smaller than a protein — that often act as signaling molecules in our bodies and help regulate the immune system, metabolism and many other critical functions. Will Stone, NPR, 8 July 2026 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

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Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 11 Jul. 2026.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

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