1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor
Examples of high-grade in a Sentence
Recent Examples on the Web
Mom Nicole Dearth told ABC News her youngest child, Crew, was diagnosed in March 2025 with a rare liver cancer, a high-grade Stage 4 hepatoblastoma that had spread to his right lung.
—
ABC News, 3 Apr. 2026
Previous research identified a problem protein, focal adhesion kinase, in several high-grade cases of ovarian cancer.
—Noah Lyons, San Diego Union-Tribune, 3 Apr. 2026
Maxwell was diagnosed with high-grade non-Hodgkin lymphoma in January 2023.
—Vanessa Etienne, PEOPLE, 30 Mar. 2026
Made from high-grade natural wood, this foldable bookcase’s four shelves offer ample storage space.
—Bestreviews, Chicago Tribune, 30 Mar. 2026
See All Example Sentences for high-grade
Examples are automatically compiled from online sources to
show current usage.
Read More
Opinions expressed in the examples do not represent those of Merriam-Webster or its editors.
Send us feedback.
ABC News, 3 Apr. 2026
Previous research identified a problem protein, focal adhesion kinase, in several high-grade cases of ovarian cancer.
—Noah Lyons, San Diego Union-Tribune, 3 Apr. 2026
Maxwell was diagnosed with high-grade non-Hodgkin lymphoma in January 2023.
—Vanessa Etienne, PEOPLE, 30 Mar. 2026
Made from high-grade natural wood, this foldable bookcase’s four shelves offer ample storage space.
—Bestreviews, Chicago Tribune, 30 Mar. 2026
See All Example Sentences for high-grade
Cite this Entry
“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 10 Apr. 2026.
Copy CitationLove words? Need even more definitions?
Merriam-Webster unabridged
