: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit

Examples of haplotype in a Sentence

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In the absence of allelic competitors this variant sweeps up in frequency extremely rapidly, and flanking regions of the genome generate a long haplotype block. Razib Khan, Discover Magazine, 13 Sep. 2013 Such hot spots of related individuals with a specific haplotype may correlate with healthy lifestyles or may not, as shown by centenarians who used alcohol or were sedentary for much of their lives. Torie Bosch, STAT, 20 June 2026 Specific combinations of these mutations—called a haplotype—seem to confer a higher risk of developing type 1 diabetes. Amanda Gardner, Health, 20 Nov. 2023 Analysis of ancient and modern human genomes, along with those of our closest relatives, revealed a common haplotype, or group of alleles (different forms of a gene), inherited together from one parent. Elizabeth Rayne, Ars Technica, 27 Dec. 2024 See All Example Sentences for haplotype

Word History

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of haplotype was in 1967

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Cite this Entry

“Haplotype.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/haplotype. Accessed 8 Jul. 2026.

Medical Definition

haplotype

noun
: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit

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