granulocyte-macrophage colony-stimulating factor

granulocyte–macrophage colony–stimulating factor

noun

Definition of GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR

: a colony-stimulating factor produced by T cells, macrophages, endothelial cells, and fibroblasts that promotes the differentiation of bone marrow stem cells, stimulates the maturation of precursor cells into granulocytes and macrophages, and activates mature macrophages—abbreviation GM-CSF; see sargramostim