: a nucleotide consisting of two units each composed of a phosphate, a pentose, and a nitrogen base

Examples of dinucleotide in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Yet the shape of the part of the protein that produces the dinucleotide cGAMP signal has remained structurally unchanged for all that time. Viviane Callier, Quanta Magazine, 15 Apr. 2026 The vitamin can help compensate for defects in the body’s ability to make a molecule, called nicotinamide adenine dinucleotide (NAD), which researchers have linked for the first time to healthy fetal development in humans. Gretchen Vogel, Science | AAAS, 9 Aug. 2017 Originally, it was thought that this protein could only be activated by cyclic GMP-AMP (cGAMP), or similar cyclic dinucleotide molecules. William A. Haseltine, Forbes, 21 Apr. 2022

Word History

First Known Use

circa 1927, in the meaning defined above

Time Traveler
The first known use of dinucleotide was circa 1927

Browse Nearby Words

Cite this Entry

“Dinucleotide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/dinucleotide. Accessed 7 Jul. 2026.

Medical Definition

dinucleotide

noun
: a nucleotide consisting of two units each composed of a phosphate, a pentose, and a purine or pyrimidine base
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!