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differentiation1 a: the act of describing a thing by giving its differentia b: the enhancement of microscopically visible differences between tissue or cell parts by partial selective decolorization or removal of excess stain (as in regressive staining) c: the development of a discriminating conditioned response with a positive response to one stimulus and absence of the response on the application of similar but discriminably different stimuli2 a: modification of different parts of the body for performance of particular functions; also : specialization of parts or organs in the course of evolution b: the sum of the developmental processes whereby apparently unspecialized cells, tissues, and structures attain their adult form and function—compare determination
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