derangement

de·range·ment

noun \di-ˈrānj-mənt\

Definition of DERANGEMENT

1

: a disturbance of normal bodily functioning or operation <derangements in the secretion of adaptive hormones—Hans Selye>

2

: insanity

—de·range \di-ˈrānj\ transitive verb, de·ranged de·rang·ing