Medical Definition of constitutive
1a: of, relating to, or being an enzyme or protein produced in relatively constant amounts in all cells of an organism without regard to cell environmental conditions (as the concentration of a substrate)—compare inducible ab: controlling production of or coding genetic information for a constitutive enzyme or protein <constitutive genes> <constitutive mutations>
2: being chromatin of a chromosomal region that is condensed into heterochromatin in all cells of an organism rather than just some
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