clonidine

noun

clo·​ni·​dine ˈklä-nə-ˌdēn  ˈklō- 

-ˌdīn

: an antihypertensive drug C₉H₉Cl₂N₃ used especially to treat essential hypertension, to prevent migraine headache, and to diminish opioid and nicotine withdrawal symptoms

Examples of clonidine in a Sentence

Recent Examples on the Web

Ferro noted that medetomidine withdrawal often requires much higher than typical doses of clonidine. — Hannah Harris Green, STAT, 26 June 2026

Additionally, authorities said the prescription medication clonidine was found in her system despite not having been prescribed to her, per the statement. — Nicole Acosta, PEOPLE, 24 June 2026

The most common blood pressure medications that can cause this are beta blockers and clonidine. — Jessica Swirble, Verywell Health, 8 June 2026

Other medications, including gabapentin and clonidine, may also be helpful in some cases. — Katia Hetter, CNN Money, 5 May 2026

Word History

Etymology

chlor- + aniline + imide + -ine entry 2

First Known Use

1969, in the meaning defined above

Rhymes for clonidine

• acridine
• acrolein
• adenine
• alkylene
• aniline
• anthracene
• aquiline
• asphaltene
• atlantean
• atrazine
• butadiene
• butylene

Medical Definition

clonidine

noun

clo·​ni·​dine ˈklän-ə-ˌdēn  ˈklōn- 

-ˌdīn

: an antihypertensive drug used in the form of its hydrochloride C₉H₉Cl₂N₃·HCl especially to treat essential hypertension, to prevent migraine headache, and to diminish opiate withdrawal symptoms