Medical Definition of cholinesterase
1: an enzyme that occurs chiefly at neuromuscular junctions and promotes the hydrolysis of acetylcholine at postsynaptic receptors : acetylcholinesterase <The acetylcholine released by cholinergic fibers is rapidly decomposed by the action of cholinesterase.—John W. Hole, Human Anatomy & Physiology, 1981> <As a cholinesterase inhibitor, it increases parasympathetic nervous system activity.—T. A. Farley et. al., The Journal of the American Medical Association, 2 June 1999>
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