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bolus1: a rounded mass: as a: a large pill b: a soft mass of chewed food2 a: a dose of a substance (as a drug) given intravenously b: a large dose of a substance given by injection for the purpose of rapidly achieving the needed therapeutic concentration in the bloodstream <the patient receives a bolus dose to reach the minimum effective analgesic concentration — J. F. Camp> <subcutaneous injection of a premeal bolus of fast-acting insulin>
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