Medical Definition of bolus
1: a rounded mass: asa: a large pillb: a soft mass of chewed food
2a: a dose of a substance (as a drug) given intravenouslyb: a large dose of a substance given by injection for the purpose of rapidly achieving the needed therapeutic concentration in the bloodstream <the patient receives a bolus dose to reach the minimum effective analgesic concentration—J. F. Camp> <subcutaneous injection of a premeal bolus of fast-acting insulin>
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