Medical Definition of alteplase
: a recombinant form of tissue plasminogen activator that is used to prevent damage to heart muscle following a heart attack and to reduce neurological damage following ischemic stroke <Intravenous thrombolytic treatment with alteplase, initiated within 3 hours after the onset of symptoms, is the only medical therapy currently available for acute ischemic stroke.—Werner Hacket et al., The New England Journal of Medicine, 25 Sept. 2008> ◆Alteplase is marketed under the trademark Activase.
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