: any of numerous usually colorless, complex, and bitter organic bases (such as morphine or caffeine) containing nitrogen and usually oxygen that occur especially in seed plants and are typically physiologically active

Examples of alkaloid in a Sentence

Recent Examples on the Web
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Mitragynine is a naturally occurring alkaloid that can be isolated from the leaves of Mitragyna speciosa, a medicinal plant also known as kratom, according to the National Center for Biotechnology Information’s National Library of Medicine. — Althea Legaspi, Rolling Stone, 17 Sep. 2026 Mitragynine is an alkaloid that occurs in trace amounts in the leaves of the kratom tree, Mitragyna speciosa, prevalent in Southeast Asia. — Theresa Braine, New York Daily News, 16 Sep. 2026 Many scientists believe the drug’s primary neuroactive alkaloid, called arecoline, is only noticeable after chewing betel nuts processed with slaked lime. — Andrew Paul, Popular Science, 10 Sep. 2026 No self-respecting living thing would deliberately sniff, let alone eat, any part of the plant, which also contains highly toxic steroidal alkaloids. — ABC News, 8 Sep. 2026 See All Example Sentences for alkaloid

Word History

First Known Use

1820, in the meaning defined above

Time Traveler
The first known use of alkaloid was in 1820

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Cite this Entry

“Alkaloid.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/alkaloid. Accessed 28 Sep. 2026.

Medical Definition

: any of numerous usually colorless, complex, and bitter organic bases (as morphine or caffeine) containing nitrogen and usually oxygen that occur especially in seed plants and are typically physiologically active

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