Lou Gehrig's disease

noun

Lou Geh·​rig's disease ˌlü-ˈger-igz- 

: amyotrophic lateral sclerosis

Examples of Lou Gehrig's disease in a Sentence

Recent Examples on the Web

The condition, also known as Lou Gehrig's disease, leads to muscle weakness, as well as loss of mobility and speech. — Abigail Adams, PEOPLE, 19 May 2026

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is a disease of the nervous system that affects the brain and spinal cord and causes loss of muscle control, according to Mayo Clinic. — Swasti Singhai, USA Today, 19 May 2026

Dane receives more screen time, but his dissolute, oft-drunk character is hard to watch knowing the actor’s offscreen battle with amyotrophic lateral sclerosis, also known as Lou Gehrig's disease. — Carla Meyer, San Francisco Chronicle, 8 Apr. 2026

Genetic testing shows the 32-year-old has the same form of ALS — Lou Gehrig's disease — that killed her 42-year-old father in 2024. — Stephanie Stahl, CBS News, 9 Mar. 2026

Word History

Etymology

Lou Gehrig †1941 American baseball player who suffered from the disease

First Known Use

1939, in the meaning defined above

Rhymes for Lou Gehrig's disease

• ferromanganese
• mephistopheles
• abcs
• absentees
• addressees
• adoptees
• allottees
• amputees
• antifreeze
• appellees
• appointees
• arrestees

Medical Definition

Lou Gehrig's disease

noun

Lou Geh·​rig's disease ˌlü-ˌge(ə)r-igz-, -ˌga(ə)r- 

: amyotrophic lateral sclerosis