end-stage

adjective

ˈend-ˌstāj 

: being or occurring in the final stages of a terminal disease or condition

end-stage renal disease

Examples of end-stage in a Sentence

Recent Examples on the Web

The feat could open the door to more transplants for people living with HIV who have end-stage organ disease. — Tanya Lewis, Scientific American, 19 June 2026

Many of these individuals are battling end-stage liver, kidney, or heart disease, hoping for a call that will change—or save—their lives. — Dr. Hiroshi Sogawa, Hartford Courant, 20 Apr. 2026

Troy was ultimately diagnosed with end-stage kidney disease due to hypertension. — Erin Clack, PEOPLE, 16 May 2026

Nilsson battled end-stage kidney disease for more than four years and received dialysis three days a week, according to a family post on his Facebook page. — Melissa Ruggieri, USA Today, 3 July 2026

Word History

First Known Use

1920, in the meaning defined above

Rhymes for end-stage

• assuage
• backstage
• bocage
• downstage
• engage
• enrage
• leafage
• messuage
• offstage
• onstage
• outrage
• pelage

Medical Definition

end-stage

adjective

ˈend-ˌstāj 

: being or occurring in the final stages of a terminal disease or condition

end-stage liver failure