zymogen


zy·mo·gen

noun \ˈzī-mə-jən\

Definition of ZYMOGEN

:  an inactive protein precursor of an enzyme secreted by living cells and converted (as by a kinase or an acid) into an active form —called also proenzyme

Origin of ZYMOGEN

International Scientific Vocabulary
First Known Use: 1877

zy·mo·gen

noun \ˈzī-mə-jən\   (Medical Dictionary)

Medical Definition of ZYMOGEN

: an inactive protein precursor of an enzyme secreted by living cells and converted (as by a kinase or an acid) into an active form—called also proenzyme

zymogen

noun    (Concise Encyclopedia)

Any of a class of proteins that are secreted by cells and are inactive precursors of enzymes. Transformation into active enzymes occurs as one or more peptide bonds in the zymogen are cleaved. Examples include trypsinogen and chymotrypsinogen, secreted by the pancreas and converted by proteolysis in the small intestine into the active enzymes trypsin and chymotrypsin; and numerous coagulation factors.

Variants of ZYMOGEN

zymogen or proenzyme

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