Definition of vicissitude
1 a : the quality or state of being changeable : mutability b : natural change or mutation visible in nature or in human affairs
2 a : a favorable or unfavorable event or situation that occurs by chance : a fluctuation of state or condition <the vicissitudes of daily life> b : a difficulty or hardship attendant on a way of life, a career, or a course of action and usually beyond one's control c : alternating change : succession
Origin of vicissitude
Middle French, from Latin vicissitudo, from vicissim in turn, from vicis change, alternation — more at week
First Known Use: circa 1576
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