vicissitude
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vi·cis·si·tude

noun \və-ˈsi-sə-ˌtüd, vī-, -ˌtyüd\

Definition of VICISSITUDE

1
a : the quality or state of being changeable : mutability
b : natural change or mutation visible in nature or in human affairs
2
a : a favorable or unfavorable event or situation that occurs by chance : a fluctuation of state or condition <the vicissitudes of daily life>
b : a difficulty or hardship attendant on a way of life, a career, or a course of action and usually beyond one's control
c : alternating change : succession

Origin of VICISSITUDE

Middle French, from Latin vicissitudo, from vicissim in turn, from vicis change, alternation — more at week
First Known Use: circa 1576

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