Inflammation of the uvea, the middle coat of the eyeball. Anterior uveitis, involving the iris or ciliary body (containing the muscle that adjusts the lens) or both, can lead to glaucoma and blindness. Posterior uveitis, involving the choroid (which contains the eye's blood supply), can cause bleeding, lens clouding, and eyeball atrophy. Granulomatous uveitis (persistent inflammation with a grainy surface) causes vision impairment, pain, watery eyes, and sensitivity to light; nongranulomatous uveitis causes less pain and sensitivity, with a better chance of recovery. Causes include generalized infections and other diseases, allergic reactions, and injury. Rarely, the uninjured eye also has symptoms, with a risk of blindness in both eyes. Treatment aims to eliminate infection, reduce inflammation, and preserve vision.