tricyclic antidepressant


tricyclic antidepressant

noun

Definition of TRICYCLIC ANTIDEPRESSANT

:  any of a group of antidepressant drugs (as imipramine and amitriptyline) that contain three fused benzene rings, potentiate the action of catecholamines (as norepinephrine and serotonin) by inhibiting their uptake by nerve endings, and do not inhibit the action of monoamine oxidase —called also tricyclic

First Known Use of TRICYCLIC ANTIDEPRESSANT

1966

tricyclic antidepressant

noun    (Medical Dictionary)

Medical Definition of TRICYCLIC ANTIDEPRESSANT

: any of a group of antidepressant drugs (as imipramine, amitriptyline, desipramine, and nortriptyline) that contain three fused benzene rings, that potentiate the action of catecholamines (as norepinephrine and serotonin) by inhibiting their uptake by nerve endings, and that do not inhibit the action of monoamine oxidase

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