treph·i·na·tion noun \ˌtre-fə-ˈnā-shən\
: an act or instance of perforating the skull with a surgical instrument
First Known Use of TREPHINATION
treph·i·na·tion noun \ˌtref-ə-ˈnā-shən\ (Medical Dictionary)
: an act or instance of using a trephine (as to perforate the skull)
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