1
: of or relating to a synapsis
2
: of or relating to a synapse

Examples of synaptic in a Sentence

Recent Examples on the Web
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In a patient with epileptic encephalopathy, Atlas pointed the scientists to a variant in DNM1, a gene important to synaptic function in brain cells. — Jeremy Kahn, Fortune, 8 Sep. 2026 The team used this to look specifically at engram synapses, specialized synaptic connections between memory-storing neurons. — Jacek Krywko, ArsTechnica, 22 Aug. 2026 This property, called synaptic plasticity, meant the researchers could train their acoustic synapse to perform a range of tasks. — IEEE Spectrum, 18 June 2026 Maybe there’s a way to hack the algorithm constructively, to create virtual synaptic connections that don’t quite exist yet. — Alma Rota, Rolling Stone, 17 June 2026 See All Example Sentences for synaptic

Word History

Etymology

New Latin synapsis

First Known Use

1895, in the meaning defined at sense 1

Time Traveler
The first known use of synaptic was in 1895

Cite this Entry

“Synaptic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/synaptic. Accessed 2 Oct. 2026.

Medical Definition

synaptic

adjective
syn·​ap·​tic
si-ˈnap-tik, British also sī-
1
: of, relating to, or participating in synapsis
synaptic chromosomes
2
: of or relating to a synapse
synaptic transmission
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