sulfa drug


sulfa drug

noun

Definition of SULFA DRUG

:  any of various synthetic organic bacteria-inhibiting drugs that are sulfonamides derived especially from sulfanilamide

First Known Use of SULFA DRUG

1940

sulfa drug

noun    (Medical Dictionary)

Medical Definition of SULFA DRUG

: any of various synthetic organic bacteria-inhibiting drugs that are sulfonamides closely related chemically to sulfanilamide—called also sulfa

sulfa drug

noun    (Concise Encyclopedia)

Common term for sulfonamide drug, any member of a class of synthetic antibacterial drugs with a particular chemical structure including both sulfur and nitrogen atoms. Their effectiveness against bacteria was discovered in 1932 by Gerhard Domagk, and they became the first chemical substances systematically used against human bacterial infections. Sulfa drugs inhibit the growth and multiplication of certain bacteria (but do not kill them) by interfering with the synthesis of folic acid. Because of their toxicity and growing bacterial resistance, sulfa drugs are no longer in common use (except for urinary-tract infections, certain forms of malaria, and preventing infection of burns), having been largely superseded by less toxic antibiotics.

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