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smallpoxOne entry found. Main Entry: small·pox Pronunciation: \ˈsmȯl-ˌpäks\ Function: noun Date: 1518 : an acute contagious febrile disease of humans that is caused by a poxvirus (species Variola virus of the genus Orthopoxvirus), is characterized by a skin eruption with pustules, sloughing, and scar formation, and is believed to have been eradicated globally by widespread vaccination —called also variola
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