second-line
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sec·ond–line

adjective \ˈse-kən(d)-ˈlīn\

Definition of SECOND-LINE

: not being the usual or preferred choice <second–line drugs to treat tuberculosis> — compare first-line

First Known Use of SECOND-LINE

1991

sec·ond–line

adjective \ˌsek-ən(d)-ˌlīn\   (Medical Dictionary)

Medical Definition of SECOND–LINE

: being or using a drug that is not the usual or preferred choice—compare first-line

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