quadrivalent

1 of 2

adjective

quad·​ri·​va·​lent ˌkwä-drə-ˈvā-lənt 

in sense 2

kwä-ˈdri-və-lənt 

1

: tetravalent

2

: composed of four homologous chromosomes synapsed in meiotic prophase

quadrivalent

2 of 2

noun

: a quadrivalent chromosomal group

Examples of quadrivalent in a Sentence

Recent Examples on the Web

Adjective

For the majority of those aged 6 months and older, the CDC recommends receiving the standard quadrivalent flu vaccine, which protects against four different strains of the virus. — Mary Kekatos, ABC News, 22 Nov. 2023

But the makers of quadrivalent vaccines largely only have licenses to make quadrivalent vaccines—not trivalent ones. — Beth Mole, Ars Technica, 5 Oct. 2023

Noun

That could effectively open up one of the seats in the vaccines, dropping them next season from quadrivalent formulations – targeting four different antigens in a single shot – to trivalent. — Alexander Tin, CBS News, 29 Feb. 2024

Then the quadrivalent Gardasil was administered until 2023, when the nonavalent Gardasil 9 was introduced. — Annalisa Merelli, STAT, 25 Jan. 2024

Word History

Etymology

Adjective

International Scientific Vocabulary

First Known Use

Adjective

1865, in the meaning defined at sense 1

Noun

1923, in the meaning defined above

Rhymes for quadrivalent

• hexavalent
• monovalent
• multivalent
• pentavalent
• polyvalent
• tetravalent
• univalent
• assailant
• covalent
• divalent
• inhalant

Medical Definition

quadrivalent

1 of 2 adjective

quad·​ri·​va·​lent

ˌkwäd-rə-ˈvā-lənt, in sense 2 kwä-ˈdriv-ə-lənt

1

: tetravalent

2

: composed of four homologous chromosomes synapsed in meiotic prophase

quadrivalent

2 of 2 noun

: a quadrivalent chromosomal group