quadrivalent

1 of 2

adjective

quad·​ri·​va·​lent ˌkwä-drə-ˈvā-lənt How to pronounce quadrivalent (audio)
in sense 2
kwä-ˈdri-və-lənt How to pronounce quadrivalent (audio)
1
2
: composed of four homologous chromosomes synapsed in meiotic prophase

quadrivalent

2 of 2

noun

: a quadrivalent chromosomal group

Examples of quadrivalent in a Sentence

Recent Examples on the Web
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Adjective
For the majority of those aged 6 months and older, the CDC recommends receiving the standard quadrivalent flu vaccine, which protects against four different strains of the virus. Mary Kekatos, ABC News, 22 Nov. 2023 After years of work, the first quadrivalent shots began to roll out in 2012. Helen Branswell, STAT, 5 Oct. 2023
Noun
That could effectively open up one of the seats in the vaccines, dropping them next season from quadrivalent formulations – targeting four different antigens in a single shot – to trivalent. Alexander Tin, CBS News, 29 Feb. 2024 Then the quadrivalent Gardasil was administered until 2023, when the nonavalent Gardasil 9 was introduced. Annalisa Merelli, STAT, 25 Jan. 2024 See All Example Sentences for quadrivalent

Word History

Etymology

Adjective

International Scientific Vocabulary

First Known Use

Adjective

1865, in the meaning defined at sense 1

Noun

1923, in the meaning defined above

Time Traveler
The first known use of quadrivalent was in 1865

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Cite this Entry

“Quadrivalent.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/quadrivalent. Accessed 10 Sep. 2025.

Medical Definition

quadrivalent

1 of 2 adjective
quad·​ri·​va·​lent
ˌkwäd-rə-ˈvā-lənt, in sense 2 kwä-ˈdriv-ə-lənt
1
2
: composed of four homologous chromosomes synapsed in meiotic prophase

quadrivalent

2 of 2 noun
: a quadrivalent chromosomal group
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