prion

3 ENTRIES FOUND:

1pri·on

noun \ˈprī-ˌän\

Definition of PRION

:  any of several small petrels (genus Pachyptila of the family Procellariidae) of the southern hemisphere that are bluish gray above and white below

Origin of PRION

New Latin, from Greek priōn saw, from priein to saw; from its sawlike bill
First Known Use: 1848

Rhymes with PRION

aeon, add-on, agon, agone, Akan, Ambon, Amman, anon, Anshan, archon, argon, Argonne, atman, axon, bank on, barchan, baton, big on, Bion, blouson, bon ton, bonbon, boron, boson, bouillon, bring on, build on, bygone, caisson, call on, canton, capon, cast on, catch on, Ceylon, chaconne, Charon, chew on, chiffon, chiton, chrismon, Cimon, cistron, clip-on, codon, come-on, cordon, coupon, crampon, crayon, crepon, cretonne, crouton, Dacron, dead-on, Dear John, doggone, Dogon, Don Juan, exon, fall on, flacon, foregone, form on, Freon, fronton, futon, Garonne, get on, Gibran, gluon, gnomon, go on, guidon, hadron, Hainan, hand on, hands-on, hang on, have on, hazan, head-on, Henan, hereon, high on, hit on, hogan, hold on, Huainan, icon, intron, ion, jargon, Jinan, jomon, kanban, kaon, Kashan, keen on, Khoisan, Kirman, koan, krypton, kurgan, Kurgan, lauan, lepton, let on, lock on, log on, look on, Luzon, macron, Masan, Medan, Memnon, meson, micron, Milan, mod con, moron, mouton, Multan, muon, natron, nekton, neon, nephron, neuron, neutron, ninon, Nippon, nylon, odds-on, Oman, Oran, Orlon, paeon, parton, Pathan, pavane, pecan, peon, Phaëthon, photon, phyton, pick on, pion, piton, plankton, pluton, pompon, proton, Pusan, push on, put-on, pylon, python, racon, radon, rag on, rayon, recon, rhyton, run-on, run on, Saint John, Saipan, salon, San Juan, Schliemann, Schumann, Shaban, shaman, shaitan, Shingon, sign on, sit on, slip-on, snap-on, solon, Solon, soupçon, soutane, stand on, stolon, stuck on, Suwon, sweet on, Taiwan, taipan, take on, tampon, taxon, Teflon, Tehran, teston, thereon, Tian Shan, tisane, torchon, toucan, toyon, trade on, trigon, Tristan, triton, trogon, try on, Tucson, turned-on, turn on, Typhon, tzigane, uhlan, Ulsan, upon, wait on, walk-on, witan, whereon, Wonsan, wonton, work on, Wuhan, xenon, Xi'an, Yukon, Yunnan, zircon

2pri·on

noun \ˈprē-ˌän\

Definition of PRION

:  any of several protein particles that are abnormal forms of normal cellular proteins, that lack nucleic acid, and that in mammals have been implicated as the cause of prion diseases when accumulated in the mammalian brain

Origin of PRION

proteinaceous + infectious + 2-on
First Known Use: 1982

pri·on

noun \ˈprē-ˌän\   (Medical Dictionary)

Medical Definition of PRION

: any of various infectious proteins that are abnormal forms of normal cellular proteins, that proliferate by inducing the normal protein to convert to the abnormal form, and that in mammals include pathogenic forms which arise sporadically, as a result of genetic mutation, or by transmission (as by ingestion of infected tissue) and which upon accumulation in the brain cause a prion disease

prion

noun    (Concise Encyclopedia)

Disease-causing agent, discovered by Stanley Prusiner, responsible for various fatal neurodegenerative diseases called transmissible spongiform encephalopathies. An abnormal form of a normally harmless protein found in mammals and birds, the disease-causing prion can enter the brain through infection, or it can arise from a mutation in the gene that encodes the protein. Once present in the brain it causes normal proteins to refold into the abnormal shape. As prion proteins multiply, they accumulate within nerve cells, destroying them and eventually causing brain tissue to become riddled with holes. Diseases caused by prions include Creutzfeldt-Jakob disease, mad cow disease, and scrapie. Prions are unlike all other known disease-causing organisms in that they appear to lack nucleic acid (DNA or RNA).

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