prefrontal cortex
noun
: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning
Examples of prefrontal cortex in a Sentence
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The prefrontal cortex is the region of the brain responsible for judgment, decision-making and impulse control.
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Joanna Fong-Isariyawongse, The Conversation, 11 June 2026
Concentration burns glucose, decision-making depletes mental energy reserves, and by mid-afternoon, the prefrontal cortex is operating at a fraction of its morning capacity.
—William Jones
june 8, Fort Worth Star-Telegram, 8 June 2026
That’s because problem-solving, logical planning and abstract thinking are all carried out by a key region of the brain known as the prefrontal cortex, which is notoriously inflexible.
—David Cox, NBC news, 4 June 2026
These areas included the prefrontal cortex, cingulate cortex, parietal and temporal cortices, and the amygdala, which are involved in pain processing, emotional regulation, and cognition.
—Stephanie Anderson Witmer, Health, 2 June 2026
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Joanna Fong-Isariyawongse, The Conversation, 11 June 2026
Concentration burns glucose, decision-making depletes mental energy reserves, and by mid-afternoon, the prefrontal cortex is operating at a fraction of its morning capacity.
—William Jones
june 8, Fort Worth Star-Telegram, 8 June 2026
That’s because problem-solving, logical planning and abstract thinking are all carried out by a key region of the brain known as the prefrontal cortex, which is notoriously inflexible.
—David Cox, NBC news, 4 June 2026
These areas included the prefrontal cortex, cingulate cortex, parietal and temporal cortices, and the amygdala, which are involved in pain processing, emotional regulation, and cognition.
—Stephanie Anderson Witmer, Health, 2 June 2026
See All Example Sentences for prefrontal cortex
Cite this Entry
“Prefrontal cortex.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prefrontal%20cortex. Accessed 17 Jun. 2026.
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