prefrontal cortex

noun

: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning

Examples of prefrontal cortex in a Sentence

Recent Examples on the Web During these 25-minute sessions, half of the veterans simultaneously received painless, 2 milliamp tDCS stimulations directed at their ventromedial prefrontal cortex. Andrew Paul, Popular Science, 7 Mar. 2024 One 2015 study found that people hearing gossip showed more activity in their prefrontal cortex—the part of the brain responsible for navigating complex social behaviors. Daisy Jones, Vogue, 4 Mar. 2024 Studies have shown that THC, one of the main cannabinoids found in cannabis, can significantly reduce rates of anxiety and traumatic memories related to trauma and PTSD by reducing activity in the amygdala and reduces cognitive distractions by inhibiting activity in the prefrontal cortex. Sarah Sinclair, Forbes, 29 Mar. 2024 Unfortunately, post-traumatic stress disorder often reworks the brain by limiting the ventromedial prefrontal cortex’s ability to control regions like the amygdala. Andrew Paul, Popular Science, 7 Mar. 2024 The prefrontal cortex is an area of the brain involved in impulse control, decision-making and emotional regulation. Seena Mathew, Discover Magazine, 14 Dec. 2023 The dreams in this stage often seem illogical because parts of the brain's prefrontal cortex, which controls rational thought, are offline while brain regions controlling vision, movement and emotions remain active. Ingrid Wickelgren, Scientific American, 20 Feb. 2024 The researchers observed that the men’s brain post-tear sniff exhibited less activity in the prefrontal cortex and the left anterior insula, regions that are associated with aggression and decision-making. Rachel Nuwer, Scientific American, 21 Dec. 2023 All six individuals who received this stimulation in the prefrontal cortex after the night the electrode was live compared with their memory after undisturbed sleep, the scientists reported in 2023. Ingrid Wickelgren, Scientific American, 20 Feb. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'prefrontal cortex.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1900, in the meaning defined above

Time Traveler
The first known use of prefrontal cortex was in 1900

Dictionary Entries Near prefrontal cortex

Cite this Entry

“Prefrontal cortex.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prefrontal%20cortex. Accessed 25 Apr. 2024.

Medical Definition

prefrontal cortex

noun
: the gray matter of the anterior part of the frontal lobe that is highly developed in humans and plays a role in the regulation of complex cognitive, emotional, and behavioral functioning
Last Updated: - Updated example sentences
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