Definition of pepo
: an indehiscent fleshy one-celled many-seeded berry (as a pumpkin, squash, melon, or cucumber) that has a hard rind and is the characteristic fruit of the gourd family
Medical Definition of pepo
: the dried ripe seeds of the pumpkin (Cucurbita pepo) used as an anthelmintic and taeniafuge—called also pumpkin seed
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