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node of Ranvier

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node of Ran·vier \-ˈräⁿ-vē-ˌā\

Definition of node of Ranvier

  1. :  a small gap in the myelin sheath of a myelinated nerve fiber



Origin of node of ranvier

Louis A. Ranvier †1922 French histologist


First Known Use: circa 1885


Medical Dictionary

node of Ranvier

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noun node of Ran·vier \-ˈrän-vē-ˌā\

Medical Definition of node of Ranvier

  1. :  a small gap in the myelin sheath of a myelinated axon



Biographical Note for node of ranvier

Ranvier \rȧⁿ-vyā\play , Louis–Antoine (1835–1922), French histologist. Ranvier was one of the foremost histologists of his time. He is credited with transforming histology from a descriptive into an experimental science. Most of his research focused on detailed nerve and skin structure. He discovered in 1871 the interruptions of the myelin sheaths, which are now known as the nodes of Ranvier. Ranvier also produced a major study on cicatrization. With the French bacteriologist André-Victor Cornil (1837–1908) he produced a manual of histopathology that ranks as one of the landmarks of medicine in the 19th century.


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