Definition of naloxone
: a synthetic potent antagonist C19H21NO4 of narcotic drugs and especially morphine that is administered especially in the form of its hydrochloride
Origin and Etymology of naloxone
N-allyl + hydroxy- + -one
First Known Use: 1964
Medical Definition of naloxone
: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl ◆Naloxone is typically administered by injection to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.
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