multiple myeloma


multiple myeloma

noun

Definition of MULTIPLE MYELOMA

:  a disease of bone marrow that is characterized by the presence of numerous myelomas in various bones of the body

First Known Use of MULTIPLE MYELOMA

1897

multiple myeloma

noun    (Medical Dictionary)

Medical Definition of MULTIPLE MYELOMA

: a disease of bone marrow that is characterized by the presence of numerous myelomas in various bones of the body—called also myelomatosis

multiple myeloma

noun    (Concise Encyclopedia)

A malignant proliferation of abnormal plasma cells that populate the marrow-containing bones of the body. The affected plasma cells produce myeloma protein, a monoclonal antibody that replaces normal antibodies in the blood, thereby increasing susceptibility to infection and renal failure. Symptoms include pain, anemia, weakness, infection, a tendency to hemorrhage, shortness of breath, kidney insufficiency, bone fractures, and neurological symptoms. It is considered a progressive and incurable disease; treatments with thalidomide, bone-marrow transplantation, and high-dose chemotherapy may extend life span, although success rates are variable.

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