molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
a molecule of political honestyTime

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The molecule is already utilized in antibacterial medications used for the treatment of wounds and acne. New Atlas, 15 Aug. 2025 Together, the algorithms generated more than 10 million candidate molecules, none of which had ever existed before. IEEE Spectrum, 14 Aug. 2025 As the probes twinkle on and off, computational models estimate exactly where each molecule is located—and reconstruct a high-resolution image of the sample. Katarina Zimmer, JSTOR Daily, 14 Aug. 2025 After conducting experiments on mice, the researchers found that S. mansoni produces molecules that suppress the activity of TRPV1+, a protein used to send signals that the brain interprets as heat, itching or pain. Hannah Millington, MSNBC Newsweek, 13 Aug. 2025 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

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Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 20 Aug. 2025.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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