methamphetamine

noun

meth·​am·​phet·​amine ˌme-tham-ˈfe-tə-ˌmēn 

-thəm-,

-mən

: a synthetic or semisynthetic compound C₁₀H₁₅N that stimulates the central nervous system, is used medically in the form of its crystalline hydrochloride C₁₀H₁₅N·HCl especially to treat attention deficit hyperactivity disorder and obesity, and that is often abused illicitly for its stimulant properties

… methamphetamine is a powerful addictive stimulant whose longtime consumers tend to suffer from paranoia, depression, hallucinations, and violent rages.

—William Finnegan

called also meth, methedrine, speed

compare crystal meth

Examples of methamphetamine in a Sentence

Recent Examples on the Web

Cobb is serving a 22- to 28-year sentence after pleading guilty to multiple charges, including second-degree murder and driving while under the influence of methamphetamine and sedatives. —Charlotte Observer, 2 Sep. 2025

Officers recovered two handguns, methamphetamine and fentanyl, according to the probable cause statement. —Judy L. Thomas, Kansas City Star, 1 Sep. 2025

Officers searched the residence two days after the incident and found nearly 14 grams of methamphetamine, according to the complaint. —Trent Abrego, Twin Cities, 30 Aug. 2025

The program tests for various drugs, including cocaine, methamphetamine, fentanyl and other opioids, as well as xylazine, an animal tranquilizer that authorities have warned is increasingly being found mixed in with other drugs. —Michael Ruiz, FOXNews.com, 29 Aug. 2025

Word History

First Known Use

1949, in the meaning defined above

Phrases Containing methamphetamine

• crystal methamphetamine

Kids Definition

methamphetamine

noun

meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn 

: a drug derived from amphetamine that is often used illegally as a stimulant of the central nervous system

Medical Definition

methamphetamine

noun

meth·​am·​phet·​amine ˌmeth-am-ˈfet-ə-ˌmēn, ˌmeth-əm-, -mən 

: an amine C₁₀H₁₅N that is used medically in the form of its crystalline hydrochloride C₁₀H₁₅N·HCl especially to treat attention deficit hyperactivity disorder and obesity and that is often abused illicitly as a stimulant

called also meth, methedrine, methylamphetamine, speed