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Definition of LYMPH NODE
: any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph passing through the node
: any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph passing through the node—called also lymph gland
Small, rounded mass of lymphoid tissue contained in connective tissue. They occur all along lymphatic vessels, with clusters in certain areas (e.g., neck, groin, armpits). They filter bacteria and other foreign materials out of lymph and expose them to lymphocytes and macrophages that can engulf them; these cells multiply in response to accumulation of such materials, which is why lymph nodes swell during infections. The nodes also produce lymphocytes and antibodies, to be carried by lymph throughout the lymphatic system. In Hodgkin disease and other lymphomas, malignant lymph cells proliferate, causing lymph node enlargement. Other cancers often invade lymphatic vessels, which can carry cells from the tumour to lymph nodes, where they are trapped and grow into secondary tumours. Lymph nodes are therefore removed in cancer surgery to detect or prevent tumour spread.