Definition of leukotriene
: any of a group of eicosanoids that participate in allergic responses (as bronchial constriction)
First Known Use of leukotriene
Medical Definition of leukotriene
: any of a group of eicosanoids that are generated in basophils, mast cells, macrophages, and human lung tissue by lipoxygenase-catalyzed oxygenation especially of arachidonic acid and that participate in allergic responses (as bronchoconstriction in asthma)—see slow-reacting substance of anaphylaxis
Seen and Heard
What made you want to look up leukotriene? Please tell us where you read or heard it (including the quote, if possible).