isotretinoin


iso·tret·i·noin

noun \ˌī-sō-ˈtre-tə-ˌnin\

Definition of ISOTRETINOIN

:  a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne

First Known Use of ISOTRETINOIN

1980

iso·tret·i·noin

noun \ˌī-sō-ˈtret-ə-ˌnin\   (Medical Dictionary)

Medical Definition of ISOTRETINOIN

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects—see accutane

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