: a polynucleotide sequence in a nucleic acid that does not code information for protein synthesis and is removed before translation of messenger RNA compare exon

Examples of intron in a Sentence

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The coding sections of genes are interrupted by introns, which don’t encode for anything. — ArsTechnica, 4 Mar. 2026 The results from this study indicate that the murine C3a receptor structural gene is a single copy gene of approximately 8 kb comprised of 2 exons which are separated by a large intervening intron of 4724 bp. — Kirstin R.w. Matthews, STAT, 3 Feb. 2026 Several mechanisms that could create introns have been identified, and all of them may have contributed some introns to eukaryotes. — Jake Buehler, Quanta Magazine, 30 Mar. 2023 There are now about a dozen individual changes in the amino acids used to make the protein, and the nearby DNA has picked up both an insertion (an intron) and several deletions. — John Timmer, Ars Technica, 23 Feb. 2018

Word History

Etymology

intervening sequence + -on entry 2

First Known Use

1978, in the meaning defined above

Time Traveler
The first known use of intron was in 1978

Browse Nearby Words

Cite this Entry

“Intron.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/intron. Accessed 2 Oct. 2026.

Medical Definition

: a polynucleotide sequence in a nucleic acid that does not code information for protein synthesis and is removed before translation of messenger RNA compare exon

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