histidine

noun

his·​ti·​dine ˈhi-stə-ˌdēn How to pronounce histidine (audio)
: a crystalline essential amino acid C6H9N3O2 formed by the hydrolysis of most proteins

Examples of histidine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Nine essential amino acids—histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine—are available only through foods or supplements. Stacey Colino, Time, 27 May 2025 According to the study authors, the metabolites AMP and histidine were probably responsible for the signal of death that the C. elegans worms recognized. Sam Walters, Discover Magazine, 23 May 2025 High-quality protein is any protein that contains all of the nine essential amino acids (histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine) that our bodies don’t make on their own. USA TODAY, 2 July 2023 While some groups benefit from B12 and folate supplementation, less is known about L-histidine supplementation. Tamar Kane, Verywell Health, 5 Feb. 2023 This essential amino acid can help treat premature ejaculation by delaying the conversion of histidine into histamine in your body. Dallas News, 23 Dec. 2022

Word History

Etymology

International Scientific Vocabulary hist- + -idine

First Known Use

1896, in the meaning defined above

Time Traveler
The first known use of histidine was in 1896

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Cite this Entry

“Histidine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/histidine. Accessed 9 Sep. 2025.

Medical Definition

histidine

noun
his·​ti·​dine ˈhis-tə-ˌdēn How to pronounce histidine (audio)
: a crystalline essential amino acid C6H9N3O2 formed by the hydrolysis of most proteins
abbreviation His

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