International Scientific Vocabulary hist- + -idine
First Known Use: 1896
Medical Definition of HISTIDINE
: a crystalline essential amino acid C6H9N3O2 formed by the hydrolysis of most proteins—abbreviation His
One of the essential amino acids, first isolated in 1896. It occurs abundantly in hemoglobin and can be isolated from blood cells. It is used in medicine and biochemical research and as a dietary supplement and feed additive.