: of superior grade or quality <high–grade bonds>
a : being near the upper or most favorable extreme of a specified range
b : medically serious or life-threatening <a high–grade tumor>
First Known Use of HIGH-GRADE
high–grade adjective \ˈhī-ˈgrād\ (Medical Dictionary)
: being near the upper, most serious, or most life-threatening extreme of a specified range <high–grade gliomas> <high–grade cervical dysplasia>—compare low-grade
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