Definition of herpes simplex
: either of two diseases caused by herpesviruses (species Human herpesvirus 1 and Human herpesvirus 2 of the genus Simplexvirus) and marked especially by watery blisters on the skin or mucous membranes of the lips, mouth, face, or genital region
Origin of herpes simplex
New Latin, literally, simple herpes
First Known Use: 1907
Medical Definition of herpes simplex
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