heroin

noun

her·​o·​in ˈher-ə-wən How to pronounce heroin (audio)
ˈhe-rə-
: a strongly physiologically addictive narcotic C21H23NO5 that is made by acetylation of but is more potent than morphine and that is prohibited for medical use in the U.S. but is used illicitly for its euphoric effects
heroinism noun

Examples of heroin in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Both compounds bind to opioid receptors in the brain, which triggers chemical changes that, with regular use, can lead to dependence and withdrawal symptoms similar to those caused by oxycodone or heroin. Andrew Kolodny, The Conversation, 2 Apr. 2026 He was accused of running a crew that dealt crack, powder cocaine, heroin and fentanyl throughout Jamaica, Queens. John Annese, New York Daily News, 29 Mar. 2026 That binding — along with effects similar to those of opioid drugs such as heroin, fentanyl or oxycodone — has led some experts and politicians to refer to kratom as an opioid. Kristen Rogers, CNN Money, 27 Mar. 2026 The track marks littering his arms suggest a life devoted to a destructive heroin habit, but Amin’s sister is determined to nurse him back to health, even though this only puts more of a burden on the overworked single mother. Los Angeles Times, 26 Mar. 2026 See All Example Sentences for heroin

Word History

Etymology

from Heroin, a trademark

First Known Use

1898, in the meaning defined above

Time Traveler
The first known use of heroin was in 1898

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Cite this Entry

“Heroin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/heroin. Accessed 4 Apr. 2026.

Kids Definition

heroin

noun
her·​o·​in ˈher-ə-wən How to pronounce heroin (audio)
: a strongly addictive drug made from the opium poppy and stronger than morphine

Medical Definition

heroin

noun
her·​o·​in ˈher-ə-wən How to pronounce heroin (audio)
: a strongly physiologically addictive narcotic C21H23NO5 that is made by acetylation of but is more potent than morphine and that is prohibited for medical use in the United States but is used illicitly for its euphoric effects

called also acetomorphine, diacetylmorphine, diamorphine

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