Definition of hemoglobin S
: an abnormal hemoglobin that occurs in the red blood cells in sickle-cell anemia and sickle-cell trait
First Known Use of hemoglobin s
Medical Definition of hemoglobin S
: an abnormal hemoglobin occurring in the red blood cells in sickle-cell anemia and sickle-cell trait and differing from hemoglobin A in having a valine residue substituted for the glutamic-acid residue in position 6 of two of the four polypeptide chains making up the hemoglobin molecule
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