haplotype
noun
hap·lo·type
ˈha-plō-ˌtīp 
: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit
Examples of haplotype in a Sentence
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This haplotype has three copies of AMY1 and was present in samples that predated our migration out of Africa.
—
Elizabeth Rayne, Ars Technica, 27 Dec. 2024
Specific combinations of these mutations—called a haplotype—seem to confer a higher risk of developing type 1 diabetes.
—Amanda Gardner, Health, 20 Nov. 2023
In 2018, Guanchen Li and Jeremy Austin, also at the University of Adelaide, obtained the entire mitochondrial genome from hair-root material and narrowed down the maternal haplotype to H4a1a1a.
—IEEE Spectrum, 20 Mar. 2023
In a previous investigation, Pryde et al. discovered that introducing simple substitutions on a benzothiazinone molecule like compound 4 (not shown) could transform it from being a weak activator of the HAQ STING haplotype to one that was highly potent.
—William A. Haseltine, Forbes, 26 Apr. 2022
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Elizabeth Rayne, Ars Technica, 27 Dec. 2024
Specific combinations of these mutations—called a haplotype—seem to confer a higher risk of developing type 1 diabetes.
—Amanda Gardner, Health, 20 Nov. 2023
In 2018, Guanchen Li and Jeremy Austin, also at the University of Adelaide, obtained the entire mitochondrial genome from hair-root material and narrowed down the maternal haplotype to H4a1a1a.
—IEEE Spectrum, 20 Mar. 2023
In a previous investigation, Pryde et al. discovered that introducing simple substitutions on a benzothiazinone molecule like compound 4 (not shown) could transform it from being a weak activator of the HAQ STING haplotype to one that was highly potent.
—William A. Haseltine, Forbes, 26 Apr. 2022
See All Example Sentences for haplotype
Cite this Entry
“Haplotype.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/haplotype. Accessed 9 Sep. 2025.
Copy CitationMedical Definition
haplotype
noun
hap·lo·type
-ˌtīp
: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit
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