guanosine

noun

gua·​no·​sine ˈgwä-nə-ˌsēn How to pronounce guanosine (audio)
: a nucleoside C10H13N5O5 composed of guanine and ribose

Examples of guanosine in a Sentence

Recent Examples on the Web
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Previously, scientists had found that the DNA sensor cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) was driving this system-wide repair, patching up DNA double-strand breaks to stabilize the genome, but how this came to be has remained a mystery until now. New Atlas, 12 Oct. 2025 But a problem arises in people like Piqueras, whose TLR7 receptors can’t distinguish between genetic material in potentially dangerous viruses, and guanosine, a nucleic acid found in the body’s own RNA. Isabella Cueto, STAT, 18 June 2022 Although not one of the canonical RNA bases, inosine is read by the cell’s protein-translation machinery as the familiar guanosine. Sara Reardon, Scientific American, 5 Feb. 2020

Word History

Etymology

guan- (as in guanine) + ribose + -ine

First Known Use

1909, in the meaning defined above

Time Traveler
The first known use of guanosine was in 1909

Cite this Entry

“Guanosine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/guanosine. Accessed 7 Jul. 2026.

Medical Definition

guanosine

noun
gua·​no·​sine ˈgwän-ə-ˌsēn How to pronounce guanosine (audio)
: a nucleoside C10H13N5O5 composed of guanine and ribose
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